There is a CURE

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Prevention is a vaccine which we do not have. BUT we’ve got the next best thing and that is a cure. As usual we got there first and on these pages, before the pills were sucked up we told you what to get. If you were not listening that,s on you. i did my job!
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Antiviral Activity of Chloroquine against Human Coronavirus OC43 Infection in Newborn Mice
Els Keyaerts, Sandra Li, Leen Vijgen, Evelien Rysman, Jannick Verbeeck, Marc Van Ranst,* and Piet Maes

Abstract

Until recently, human coronaviruses (HCoVs), such as HCoV strain OC43 (HCoV-OC43), were mainly known to cause 15 to 30% of mild upper respiratory tract infections. In recent years, the identification of new HCoVs, including severe acute respiratory syndrome coronavirus, revealed that HCoVs can be highly pathogenic and can cause more severe upper and lower respiratory tract infections, including bronchiolitis and pneumonia. To date, no specific antiviral drugs to prevent or treat HCoV infections are available. We demonstrate that chloroquine, a widely used drug with well-known antimalarial effects, inhibits HCoV-OC43 replication in HRT-18 cells, with a 50% effective concentration (± standard deviation) of 0.306 ± 0.0091 μM and a 50% cytotoxic concentration (± standard deviation) of 419 ± 192.5 μM, resulting in a selectivity index of 1,369. Further, we investigated whether chloroquine could prevent HCoV-OC43-induced death in newborn mice. Our results show that a lethal HCoV-OC43 infection in newborn C57BL/6 mice can be treated with chloroquine acquired transplacentally or via maternal milk. The highest survival rate (98.6%) of the pups was found when mother mice were treated daily with a concentration of 15 mg of chloroquine per kg of body weight. Survival rates declined in a dose-dependent manner, with 88% survival when treated with 5 mg/kg chloroquine and 13% survival when treated with 1 mg/kg chloroquine. Our results show that chloroquine can be highly effective against HCoV-OC43 infection in newborn mice and may be considered as a future drug against HCoVs.

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Detroit automakers shutter U.S. plants in move to stop coronavirus spread

DETROIT (Reuters) – The Detroit Three automakers will shut down their U.S. plants to stop the spread of coronavirus, bowing to pressure from the union representing about 150,000 hourly workers at those facilities, industry officials said.

Ford Motor Co (F.N), General Motors Co (GM.N) and Fiat Chrysler Automobiles NV (FCHA.MI) (FCAU.N) confirmed the decisions to shut U.S. plants, as well as factories in Canada and Mexico.

The Detroit automakers’ shares took a beating on Wednesday, with GM closing 17.3% lower, Ford off 10.2% and Fiat Chrysler shares ending 9.2% lower in New York. The carmakers’ North American factories build their most profitable trucks and sport utility vehicles, such as Fiat Chrysler’s Jeep Wrangler, GM’s Chevrolet Silverado pickup and the Ford F-series truck line.

The actions come less than a day after the automakers and the United Auto Workers union agreed to keep plants running with reduced shifts and staffing, and more time allowed for cleaning.

A French Professor Reveals Chloroquine Cures And Stops The Spread Of The Coronavirus

Professor Didier Raoult, director of the Mediterranean Institute of Infection, poses for a portrait in his office at La Timone hospital in Marseille, Southern France

An acclaimed research professor in France revealed successful results of a potential treatment for COVID-19, the coronavirus.

What’s going on:

    • Professor Didier Raoult, who works for the infection hospital l’Institut Hospitalo-Universitaire (IHU) Méditerranée Infection in Marseille, published a new video in which he explained that the COVID-19 patients who were treated “with the drug chloroquine had seen a rapid and effective speeding up of their healing process, and a sharp decrease in the amount of time they remained contagious.”
    • Chloroquine has previously been used to prevent and treat malaria.
    • The drug was offered to 24 patients, who were among the first 24 to become infected in France’s southeastern region.
    • Patients were given the drug for 10 days. Researchers monitored the patients since the drug can cause severe side effects.
    • Raoult said those who did not receive the drug were still contagious after six days. Those who tried the drug were only 25% contagious, though.

Senate passes House’s coronavirus aid bill, sending it to Trump

The Senate passed the House’s coronavirus aid package on Wednesday, sending it to President Trump, who is expected to sign it. Senators voted 90-8 on the bill that passed the House in a middle-of-the-night Saturday vote but needed dozens of pages of corrections and changes, which cleared the chamber on Monday. The measure, which the Joint Committee on Taxation estimates will cost $104 billion, is the second package that Congress has passed amid growing concerns about the widespread coronavirus outbreak in the United States that has already bludgeoned the economy. The vote on the second package comes as senators are already working on “phase three,” with Senate Republicans wanting to pass next tranche next week. The third coronavirus bill is expected to include help for impacted small businesses, industries and families, including direct cash payments for Americans. McConnell has created GOP task forces for drafting the bill. Republicans briefed their colleagues during a closed-door lunch on Wednesday and are expected to hand over their work product by Thursday. The majority leader told reporters after a closed-door lunch that Republicans were “getting close” and “hoping to be together shortly.” The bill approved Wednesday bolsters unemployment insurance and guarantees free diagnostic testing for the coronavirus.It also provides up to 10 days of paid sick leave for some workers. It caps that at companies with 500 employees and would allow for those with fewer than 50 to apply for a waiver. But the bill’s path through the Senate wasn’t without drama. The House bill, which was negotiated by Speaker Nancy Pelosi (D-Calif.) and Treasury Secretary Steven Mnuchin, sparked fierce opposition from some Senate Republicans, who were largely sidelined from the talks. Senate Majority Leader Mitch McConnell (R-Ky.) tipped his hand to the frustration ahead of Wednesday’s vote. “I will vote to pass their bill. This is a time for urgent bipartisan action, and in this case, I do not believe we should let perfection be the enemy of something that will help even a subset of workers,” McConnell said. “However, the House’s bill has real shortcomings. It does not even begin to cover all of the Americans who will need help in the days ahead,” he added. Continue reading “Senate passes House’s coronavirus aid bill, sending it to Trump”

Trump invokes wartime authority of Defense Production Act to address coronavirus crisis

WASHINGTON – President Donald Trump confirmed that he plans to invoke a provision that would allow him to prohibit certain people from entering the country, including asylum seekers and those entering the country illegally at the southern border. “The answer’s yes,” Trump told reporters when asked about the code, adding that he plans to invoke it “very soon. Probably today.” The administration will invoke 42 U.S. Code 265, a section of the federal legal code that states the U.S. surgeon general “shall have the power to prohibit, in whole or in part, the introduction of persons and property from such countries or places as he shall designate in order to avert such danger, and for such period of time as he may deem necessary for such purpose.” President Donald Trump said he is invoking the Defense Production Act, which allows the administration to expedite and expand the supply of resources. Trump did not say specifically what powers he would execute, but the act could allow him to step up production of respirators and other medical equipment. Trump declined to say how, precisely, the Defense Production Act would be used and he suggested that the administration is still deciding. He said the administration had “targets” for equipment it wanted but did not say what those targets were. “We need millions of masks,” Trump said. “We need respirators.” The announcement comes as the White House and Congress negotiate a trillion-dollar economic stimulus plan to combat the impacts of the coronavirus outbreak. Continue reading “Trump invokes wartime authority of Defense Production Act to address coronavirus crisis”

A Generational War Is Brewing Over Coronavirus

Scientists say lack of alarm among young people could hinder the fight against the virus and endanger elders

Yet scientists say tests have shown children and young adults are no less likely than older people to get infected and transmit the virus. Epidemiologists are growing concerned that the millennial pushback against social-distancing measures—and an emerging generational divide about how the disease is perceived—could undo all efforts to slow the spread of the virus and put vulnerable people at high risk. President Trump on Monday stressed that young people can spread the virus even if they only have mild symptoms and recommended that Americans avoid restaurants and gatherings of more than 10 people. French President Emmanuel Macron went further, announcing a nationwide lockdown and punishment for those who violate the rules. So far, the young don’t seem to be listening.

Medical impact of coronavirus becomes clearer as experts’ research continues

The medical impact of the new coronavirus is coming into sharper focus as it continues its spread in what is now officially recognized as a pandemic. Its true fatality rate isn’t yet known, but it seems 10 times higher than the flu, which kills hundreds of thousands around the world each year, the United States’ top infectious disease expert told lawmakers last week. Most people have had mild to moderate illness and recovered, but the virus is more serious for those who are older or have other health problems. That’s a huge number, said Dr. Tom Frieden, a former director of the Centers for Disease Control and Prevention who now heads a global health organization. In the U.S., 60% of adults have at least one underlying health condition and 42% have two or more. “There’s still a lot that we don’t know about the virus and disease it causes, COVID-19,” he said. Most spread is from droplets produced when an infected person coughs, which are inhaled by people nearby. Transmission from touching contaminated surfaces hasn’t been shown yet, though recent tests by U.S. scientists suggest it’s possible — one reason they recommend washing your hands and not touching your face.

The virus can live in the air for several hours, up to 24 hours on cardboard and up to two to three days on plastic and stainless steel. Cleaning surfaces with solutions containing diluted bleach should kill it.

“While we are still learning about the biology of this virus, it does not appear that there is a major risk of spread through sweat,” said Julie Fischer, a Georgetown University microbiologist. The biggest concern about going to the gym is infected people coughing on others, or contaminating shared surfaces or equipment, she said. Consider avoiding large classes and peak hours and don’t go if you’re coughing or feverish, she suggests.

The risk of virus transmission from food servers is the same risk as transmission from other infected people, but “one of the concerns is that food servers, like others facing stark choices about insurance and paychecks, may be pressured to work even if they are sick,” she said.

Each infected person spreads to two or three others on average, researchers estimate. It spreads more easily than flu but less than measles, tuberculosis or some other respiratory diseases. It is not known if it spreads less easily among children, but fewer of them have been diagnosed with the disease. A study of 1,099 patients in China found that 0.9% of the cases were younger than 15.

What are the symptoms?

Continue reading “Medical impact of coronavirus becomes clearer as experts’ research continues”

Trump wants German coronavirus vaccine only for US

Berlin is trying to stop Washington from persuading a German company seeking a coronavirus vaccine to move its research to the US, prompting German politicians to insist no country should have a monopoly on any future vaccine. Germany’s Health Ministry confirmed a report in newspaper Welt am Sonntag, which said President Donald Trump had offered funds to lure the company CureVac to the US, and the German government was making counter-offers to tempt it to stay. “The German government is very interested in ensuring that vaccines and active substances against the new coronavirus are also developed in Germany and Europe,” the newspaper quoted a Health Ministry official as saying. “In this regard, the government is in intensive exchange with the company CureVac.” Contacted by Reuters, a spokeswoman for the German Health Ministry said: “We confirm the report in the Welt am Sonntag.”

Scientists stumble on potential vaccine by ‘pure luck’ Welt am Sonntag quoted an unidentified German government source as saying Trump was trying to secure the scientists’ work exclusively, and would do anything to get a vaccine for the United States, “but only for the United States”. Continue reading “Trump wants German coronavirus vaccine only for US”

Trump doesn’t have coronavirus – WH physician

United States President Donald Trump’s coronavirus test came back negative, his personal physician revealed on Saturday. Earlier in the day, the president confirmed he took the test and that he expected the results in a day or two. According to Conley, the test was performed Friday night and the president “remains symptom-free.” Trump hosted a delegation from Brazil at Mar-a-Lago last weekend, including Brazil’s President Jair Bolsonaro and his press secretary Fabio Wajngarten, the latter of whom was confirmed as infected with the coronavirus. Bolsonaro was first reported to be infected as well, however, he later rebuffed the claims on his Facebook page.