April 21 (Reuters) – A second wave of the coronavirus is expected to hit the United States next winter and could strike much harder than the first because it would likely arrive at the start of influenza season, the director of the Centers for Disease Control and Prevention warned on Tuesday. “There’s a possibility that the assault of the virus on our nation next winter will actually be even more difficult than the one we just went through,” CDC Director Robert Redfield told the Washington Post in an interview. As the current outbreak continues to taper off, as shown by a recent decline in hospitalization rates and other indicators, authorities need to prepare for a probable resurgence in the months ahead. “We’re going to have the flu epidemic and the coronavirus epidemic at the same time,” he said, and the combination would put even greater strain on the nation’s healthcare system than the first outbreak. The virus, which causes a highly contagious and potentially fatal respiratory illness dubbed COVID-19, emerged late last year in central China. The first known U.S. infection, a travel-related case, was diagnosed on Jan. 20 in Washington state near Seattle. Since then, nearly 810,000 people have tested positive in the United States, and more than 45,000 have died from the disease. Redfield and other public health authorities credit drastic stay-at-home orders and widespread business and school closings across the country for slowing the spread of infections. But the restrictions have also stifled American commerce while throwing at least 22 million people out of work over the past four weeks. Even as the lockdown is gradually eased, Redfield stressed the importance of individuals continuing to practice social distancing among one another. At the same time, he said, public health authorities must vastly ramp up a testing system to identify those who are infected and to locate their close personal interactions through contact tracing. Asked about the recent flurry of street protests of stay-at-home orders and calls for states to be “liberated” from such restrictions – as President Donald Trump has advocated on Twitter – Redfield told the Post: “It’s not helpful.” Building a nationwide contact tracing network, key to preventing newly diagnosed cases from growing into large outbreaks, poses a major challenge because it is so labor intensive, requiring a workforce that by some estimates would require as many as 300,000 personnel. Redfield said the CDC is discussing with state officials the possibility of enlisting and training workers from the U.S. Census Bureau, and volunteers from Peace Corps and AmeriCorps, to create a new contact tracing workforce.
Gilead disputes report that its drug flopped in coronavirus trial
(Reuters) – A closely-watched Gilead Sciences Inc (GILD.O) experimental antiviral drug failed to help patients with severe COVID-19 in a clinical trial conducted in China, but the drugmaker said the study’s results were inconclusive because it was terminated early. Gilead shares fell more than 4% after the data was inadvertently released and first reported by the Financial Times. It comes days after another report detailed rapid recovery in fever and respiratory symptoms in some patients with COVID-19 – the sometimes deadly respiratory illness caused by the coronavirus – who were treated with remdesivir at the University of Chicago Medicine hospital. Interest in Gilead’s remdesivir has been high as there are currently no approved treatments or preventive vaccines for COVID-19, and doctors are desperate for anything that might alter the course of the disease that attacks the lungs and can shut down other organs in extremely severe cases. In the Chinese trial remdesivir, given by intravenous infusion, failed to improve patients’ condition or reduce the pathogen’s presence in the bloodstream, according to draft documents published accidentally by the World Health Organization (WHO). But details were thin and suggested limitations in interpreting the data that has not yet been fully reviewed. A screenshot of the WHO posting, captured by the medical news website STAT before it was taken down, said the trial enrolled 237 patients with 158 receiving remdesivir compared with 79 who got a placebo. The rate of death was similar at 13.9% for remdesivir versus 12.8% in the control group. “It’s still not that large of a study and therefore the statistics coming out of the trial aren’t exactly robust,” Mizuho analyst Salim Syed said in a research note. Gilead in a statement said the WHO posting included inappropriate characterizations of the study, which was terminated early due to low enrollment and, as a result, cannot be used to make statistically meaningful conclusions. “The study results are inconclusive, though trends in the data suggest a potential benefit for remdesivir, particularly among patients treated early in disease,” the company said without providing details to back up that assertion. Other analysts drew some conclusions anyway. “This Chinese controlled dataset will drive the prevailing view of remdesivir, which is that it likely isn’t working in severe patients,” said Raymond James analyst Steven Seedhouse. Doctors have speculated that an antiviral drug like remdesivir would likely be most effective when administered as early as possible in the course of the disease as it is designed to help keep the virus from replicating in the blood. “Once the horse is out of the barn, it is really hard to bring in,” said Dr. Kevin Grimes, an infectious disease specialist at Houston Methodist Hospital who was not involved in the study. “If you can catch it before it has left the barnyard it is a lot easier to deal with.” The WHO said the draft manuscript is undergoing peer review before it will be officially released. Gilead is testing remdesivir, which previously failed as an Ebola treatment, in multiple trials, with results from a study involving 400 patients hospitalized with severe COVID-19 expected later this month. Expectations for that trial may now be dampened somewhat by the leaked data from the Chinese study. A separate trial in China testing the drug in patients with more moderate symptoms last week was also suspended due to a lack of eligible patients.
Up to 2.7 Million in New York May Have Been Infected, Antibody Study Finds
Preliminary results from New York’s first coronavirus antibody study show nearly 14 percent tested positive, meaning they had the virus at some point and recovered, Gov. Andrew Cuomo said Thursday. That equates to 2.7 million infections statewide — more than 10 times the state’s confirmed cases. The study, part of Cuomo’s “aggressive” antibody testing launched earlier this week, is based on 3,000 random samples from 40 locations in 19 counties. While the preliminary data suggests much more widespread infection, it means New York’s mortality rate is much lower than previously thought. As of Thursday, nearly 16,000 people in New York have died of virus-related complications. With 260,000-plus confirmed cases, the mortality rate would be as high as 6 percent. With 2.7 million cases, it would be around 0.5 percent — much lower, though still much higher than the seasonal flu. Cuomo was quick to caution, though, that that the death toll was higher than even the state’s own official report — it counts deaths in hospitals and nursing homes, but not at-home deaths or other “probable” cases. In other words, the mortality rate is still hard to determine properly. New York City had a higher rate of antibodies (21.2 percent) than anywhere else in the state and accounted for 43 percent of the total tested. Long Island had a 16.7 percent positivity rate, while Westchester and Rockland counties saw 11.7 percent of their samples come up with the antibody. The rest of the state, which accounted for about a third of those studied, had a 3.6 percent positivity rate. There were early variations by race/ethnicity and age as well. Cuomo says further analysis of the antibody study findings is underway. The early estimates mirror findings from a study in Los Angeles County, California. Researchers there found COVID-19 could have been 55 times more prevalent than reported, which would mean a far lower morbidity rate than believed. Earlier Thursday, New York City Mayor Bill de Blasio unveiled stepped-up efforts to fight that battle in the five boroughs. He says his administration has sent nearly 10 million N95 and surgical masks, gowns, gloves, face shields and other PPE to the city’s 169 nursing homes in weekly distributions to date. On Thursday, he announced the city would increase its weekly shipment by at least 50 percent, adding to the over 40,000 N95s, 800,00 surgical face masks 40,000 face shields, 1.5 million gloves and 105,000 gowns or coveralls that went out last week.
Don’t bet on vaccine to protect us from Covid-19, says world health expert
Humanity will have to live with the threat of coronavirus “for the foreseeable future” and adapt accordingly because there is no guarantee that a vaccine can be successfully developed, one of the world’s leading experts on the disease has warned. The stark message was delivered by David Nabarro, professor of global health at Imperial College, London, and an envoy for the World Health Organisation on Covid-19, as the number of UK hospital deaths from the virus passed 15,000. A further 888 people were reported on Saturday to have lost their lives – a figure described by communities secretary Robert Jenrick as “extremely sobering” – while the total number who have been infected increased by 5,525 to 114,217. The latest figures, which do not include deaths in care homes and in the community, put further pressure on the government amid continuing anger among NHS workers and unions over the lack personal protective equipment (PPE) for hospital and care home staff on the front line. In late March the government’s health advisers said that if UK deaths from Coronavirus could be kept below 20,000 by the end of the pandemic, it would be a “good result” for country. But with an estimated 6,000 people having already died in care homes from Covid-19 – a figure not included in Saturday’s official tally – the 20,000 figure is likely already to have been exceeded. In an interview with The Observer Nabarro said the public should not assume that a vaccine would definitely be developed soon – and would have to adapt to the ongoing threat. “You don’t necessarily develop a vaccine that is safe and effective against every virus. Some viruses are very, very difficult when it comes to vaccine development – so for the foreseeable future, we are going to have to find ways to go about our lives with this virus as a constant threat. “That means isolating those who show signs of the disease and also their contacts. Older people will have to be protected. In addition hospital capacity for dealing with cases will have to be ensured. That is going to be the new normal for us all.” The comments came as the former UK health secretary Jeremy Hunt said the only way forward was for nations to support a new global health system that would mean far more international cooperation between governments on health issues. It would also require richer nations doing more to support the health systems of the world’s poorest countries. “I think global health security is going to be on that small but critical list of topics like climate change that we can only solve in partnership with other countries,” Hunt told The Observer. In a clear criticism of US President Donald Trump who announced last week he was putting on hold funding to the World Health Organisation (WHO) Hunt added: “Surely the lesson of coronavirus is cure not kill…It certainly does not mean cutting their funding (to the WHO). “One of the big lessons from this will be that when it comes to health systems across the world, we are only as strong as the weakest link in the chain. “Although China has rightly been criticised for covering up the virus in the early stages the situation would have been whole lot worse if this had started in Africa. International cooperation and supporting health care systems of the poorest countries has to be a top priority in terms of the lessons we need to learn.” Nabarro’s message is the second grim warning to come from senior ranks of the WHO in the last three days. On Friday, Maria Van Kerkhove, head of WHO’s emerging diseases and zoonosis unit, warned that there was no evidence that antibody tests now being developed would show if a person has immunity or is no longer at risk of becoming reinfected by the Covid-19 virus. On Saturday it emerged that doctors and nurses treating Covid-19 face shortages of protective full-length gowns for weeks to come, as anger mounts over failures to stockpile them. Gowns were not included in a stockpile list prepared for a potential flu pandemic. After The Guardian revealed new guidance from Public Health England which instructs healthcare workers to re-use disposable equipment, the GMB, which represents NHS and ambulance staff, said support was “draining away” from Health Secretary, Matt Hancock. Saffron Cordery, deputy chief executive of NHS Providers which represents many trusts, told the Observer: “We are in a situation where we think this [issue] will last a couple of weeks, which probably does just take us to May. There is a shortage of gowns which is affecting some trusts, but not all. Some have none, and are using the alternatives.” The government will attempt to gain control of the mounting PPE concerns by appointing Paul Deighton, chief executive of the London Olympics organising committee, to lead efforts to produce equipment in Britain. Ministers also announced another £1.6bn cash injection to local councils as they attempt to stem a spiraling crisis in social care that is pushing some care providers into the red. Some have been paying inflated prices for commercial protective equipment.
Iowa Sends National Guard Troops to Defend Meat Plants From Virus
(Bloomberg) — Hundreds of National Guard personnel are being activated in Iowa as coronavirus sweeps through meat-processing plants in a state that accounts for about a third of U.S. pork supply. Iowa Governor Kim Reynolds said 250 National Guard members have been moved to full-time federal duty status and could help with testing and contact tracing for workers at plants operated by Tyson Foods Inc. and National Beef Packing Co. Activating guard soldiers is the latest attempt to contain the disease, which has forced a growing number of slaughterhouses and meat-processing plants to slow or halt operations. The disruptions are stoking concerns for eventual fresh-meat shortages in grocery stores as well leaving some farmers without a market for their animals. That’s pushing down prices for hogs and cattle, while making meat more expensive. Wholesale pork posted its biggest three-day gain in six years. “At some point we’re going to have to be talking about euthanizing hogs, and we’re not that far from it,” Reynolds told reporters. “And that would be devastating, not only for the food supply but for the cost of food going forward.” The U.S. Department of Agriculture announced a $19 billion bailout to help farmers hurt by the coronavirus outbreak, including $3 billion in purchases of meat and dairy products. On Monday, JBS SA said it was closing a pork plant in Minnesota. Governor Tim Walz had raised the possibility that some workers there may have fallen ill from another outbreak at a Smithfield Foods Inc. pork plant in South Dakota. “As we all learn more about coronavirus, it is clear that the disease is far more widespread across the U.S. and in our county than official estimates indicate based on limited testing,” Bob Krebs, president of JBS USA Pork, said in a statement. “We have taken aggressive actions to keep coronavirus out of our plant and keep this critical infrastructure facility operational.”
Coronavirus began months earlier and not in Wuhan, bombshell UK report claims
https://youtu.be/xYfzyh0HwMU
Everything we thought we knew about the beginnings of the coronavirus pandemic could be wrong. A bombshell report by scientists from the University of Cambridge has cast doubt on previous beliefs about when and where Covid-19 first broke out. While coronavirus was previously believed to have originated in a wet market in Wuhan at the end of last year, new research suggests it may have actually came from further south – and began spreading among humans as early as September 2019. The team of researchers has published its extraordinary findings – which have yet to be peer-reviewed – in the journal Proceedings of the National Academy of Sciences, outlining a “network” of infections that has thrown existing knowledge into doubt. “The virus may have mutated into its final ‘human-efficient’ form months ago, but stayed inside a bat or other animal or even human for several months without infecting other individuals,” University of Cambridge geneticist Peter Forster said on Thursday.”Then, it started infecting and spreading among humans between September 13 and December 7, generating the network we present in [the journal] Proceedings of the National Academy of Sciences [PNAS].” “What we reconstruct in the network is the first significant spread among humans,” Mr Forster said. He and colleagues from several institutes analysed more than 1,000 full genome sequences of the virus. By counting the various mutations of the virus, they were able to get closer to figuring out when the first human was infected by a strain closest to a virus spread among bats. Researchers analysed strains of the virus using a phylogenetic network – an algorithm that can map the global movement of organisms through the mutation of their genes. They found hundreds of mutations, indicating that the virus may have been spreading quietly in host animals for years before finally infecting humans. A coronavirus typically acquires one mutation a month. There have been unverified reports that the virus originated in a Wuhan lab where researchers were doing work into diseases in bats, but the new study doesn’t support that. “If I am pressed for an answer, I would say the original spread started more likely in southern China than in Wuhan,” Mr Forster said. “But proof can only come from analysing more bats, possibly other potential host animals, and preserved tissue samples in Chinese hospitals stored between September and December. “This kind of research project would help us understand how the transmission happened, and help us prevent similar instances in the future.” Phylogenetic networks are generally considered reliable means of tracking genetic mutations, but the method is limited by its sample size and having to assume a mutation speed that may not be accurate. A virus can undergo transformations in unpredictable patterns during an unprecedented outbreak such as this one.
Pressure Enormous on Politicians to Reopen the Economy
US President Donald Trump gave governors a road map on Thursday for recovering from the economic pain of the coronavirus pandemic, laying out “a phased and deliberate approach” to restoring normal activity in places that have strong testing and are seeing a decrease in COVID-19 cases.
“We’re starting our life again,” Trump said during his daily press briefing. “We’re starting rejuvenation of our economy again.”
He added, “This is a gradual process.” The new guidelines are aimed at clearing the way for an easing of restrictions in areas with low transmission of the coronavirus, while keeping them in place in harder-hit locations. Places with declining infections and strong testing would begin a three-phased gradual reopening of businesses and schools, with each phase lasting at least 14 days, meant to ensure that the virus outbreak does not accelerate again. The recommendations make clear that the return to normalcy will be a far longer process than Trump initially envisioned, with federal officials warning that some social distancing measures may need to remain in place through the end of the year to prevent a new outbreak. At the earliest, the guidelines suggest that some parts of the country could see a resumption in normal commerce and social gatherings after a month of evaluating whether the easing of restrictions leads to a resurgence in virus cases. In other parts of the country, or if virus cases resume an uptick, it could be substantially longer. Trump briefed the country’s governors on the plan on Thursday afternoon, saying they were going to be responsible for deciding when it is safe to lift restrictions in their states. That was different from the tone he set earlier this week, when he said he had “total” authority on when and how the country reopened. “You’re going to call your own shots,” Trump told governors, according to an audio recording obtained by The Associated Press news agency. “We’re going to be standing alongside of you.” Meanwhile, under the federal guidelines, those most susceptible to the respiratory disease would be advised to remain sheltered in place until their area enters the final phase – and even then, they are advised to take precautions to avoid close contact with other people. The federal guidelines come after seven governors in the Midwest announced on Thursday that they would coordinate on reopening the economy, after similar pacts were announced earlier this week in the west and northeast. Trump held conference calls earlier on Thursday with legislators he named to a new congressional advisory task force. The economic costs were clear in new federal data showing that at least 22 million Americans have been thrown out of work in the last month. But the legislators repeatedly urged the president not to sacrifice public health in an effort to reopen the economy. “My highest priority on this task force will be to ensure the federal government’s efforts to reopen our economy are bipartisan, data-driven and based on the expertise of public health professionals,” said Democratic Senator Mark Warner of Virginia. Business leaders, too, raised concerns to the president in a round of calls on Wednesday, warning that a dramatic increase in testing and wider availability of protective equipment would be necessary before they could safely revive operations.
Russia’s COVID-19 infections jump by 3,448
Global Covid-19 cases over 2 million as Putin warns Russia faces ‘extraordinary’ crisis
Russian president suggests army could be drafted in as China also sounds alarm at cross-border cases. Putin Warned
“We have a lot of problems, we don’t have anything especially to brag about and we definitely mustn’t relax,” he added. He told officials they needed to “consider all scenarios for how the situation will develop, even the most complex and extraordinary”. His warning came as the number of global infections rose to more than 2 million, according to Johns Hopkins University. At least 119,678 people around the world have died, with the highest death tolls in the US and Italy. About 450,000 people have recovered. The true number of infections is likely to be higher, with suspected under-reporting or limited testing in some countries. President Alexander Lukashenko in Belarus has made the claim of zero infections or danger from the virus. In the video conference, Putin called for measures to end shortages of protective equipment for medics and added that Russia would also bring in the defence ministry to help if necessary. China has also voiced concern about spread of the virus in Russia. While China’s daily reported infection rate remains far below its peak during the pandemic, the majority of new cases have been in regions bordering its northern neighbour. The area has become the new focus of containment measures, with some lockdown measures brought in for the cities of Hubin and Suifenhe.
The End of Cash? A Pandemic is as good an excuse as any
Cash has been the target of the banking and financial elites for years. Now, the coronavirus pandemic is being used to frighten the masses into accepting a cashless society. That would mean the death of what’s left of our free society. CBS News, CNN, and other mainstream outlets are fearmongering again. Alarmism is nothing new in the media world, but this time, it’s not about triggering panic buying or even pushing a political agenda. The war on cash is about imposing a new meta-narrative. As economist Joseph Salerno explains, the cashless society forces all payments to be made through the financial system. It doesn’t end with monopoly control over transactions, though. Being bound to computers for transactions kicks the door wide open to hardcore surveillance of personal activity and location data. Being eternally on the grid means relentless taxation and negative interest rates, which the Federal Reserve is already gearing up for. None of this bothers the well-heeled boosters of a cashless society or their lackeys in the media. They want Americans reading about the threat of coronavirus cooties on their cash, which is absurd. Germs, of course, can loiter all over credit and debit cards, smartphones, ATMs, and every other cash alternative device. Too bad implanted microchip technology isn’t further along, the banksters must be thinking. In another CNN article, readers are practically shamed for withdrawing cash to save during a crisis. Every sentence, every word, every letter of the article is nuts. It begins by reassuring the reader that their bank account is insured by the Federal Deposit Insurance Corporation (FDIC). There’s no mention of moral hazard from CNN. The fact that the federal government guarantees every bank account up to $250,000 encourages reckless financial and banking behavior. Not worth mentioning, CNN? Prior to the end of World War II, there were $500, $1,000, and $10,000 bills in wide circulation. This cash was dissolved by the Federal Reserve in the name of fighting organized crime. This same argument is now being made against $50 and $100 bills by Harvard economics professor Kenneth Rogoff. In the Wall Street Journa , Rogoff also wrote that a cashless society would offer such benefits as “greater flexibility for the Federal Reserve to stimulate the economy when necessary.” He wrote those words in 2017. And these too: “The Federal Reserve should be able to implement negative nominal interest rates vastly more effectively in the absence of large bills, which could prove quite important as a stimulative tool in the next financial crisis.” Prophetic. And indeed, negative interest rates would require the assistance of outlawing cash, so that banking customers don’t cheat by simply drawing out on their accounts. Pardon the pun, but it’s absolutely sick how COVID-19 is being used now as a launching pad for this cashless agenda. There’s nothing to fear about using cash during this time of social distancing. Wash your hands after handling cash, but don’t give up your moolah. Preserve your health, your privacy, and your liberty.
Good News And Good News
Market is cooperating rather nicely and people are being healed big time with the regimen of hydroxychloroquine.