BARK BARK BARK Scientists sound alarm over new ‘worst-ever’ super-mutant COVID variant that could make vaccines 40% less effective BARK BARK BARK

UK and Israel ban travel from South Africa and five other countries but passengers will continue to stream into US
  • The B.1.1.529 variant has a ‘very unusual constellation’ of mutations and may be more resistant to the vaccine
  • Likely to be officially named Nu, variant might evade the body’s immune response and be more transmissible
  • There are currently 77 confirmed cases in South Africa, four in Botswana, one in Hong Kong and one in Israel
  • However, the real numbers are likely much higher as health authorities establish the full scale of the spread
  • Britain, Israel, Singapore, Germany and Ital are among increasing countries to block flights from South Africa
  • There are no direct flights to US from any of the countries except South Africa. Early Friday morning, the CDC still listed South Africa as ‘Level 1: Low Level of COVID-19’ on the country’s travel advice page

Scientists are growing increasingly alarmed at a new COVID-19 variant originating in Southern Africa, which on Thursday and Friday forced countries including the U.K., Israel, Italy and Germany to effectively stop travel from the region, but passengers are continuing to arrive in the U.S. Flight restrictions from South Africa to the US were lifted two weeks ago, along with restrictions on around 30 other countries. As of 5:00 a.m. on Friday, the CDC listed South Africa as ‘Level 1: Low Level of COVID-19’. The variant, B.1.1.529, is believed to have emerged in Botswana – from where there are no direct flights to the U.S. – and is also being found in neighboring South Africa. Hong Kong reported a case after a passenger who had recently traveled from South Africa was found to be infected with the variant, and then infected another person while in the same hotel, quarantining. Israel has also identified a case ‘in a person who returned from Malawi,’ with ‘two more cases of people returning from abroad’ placed in quarantine, the country’s health ministry said Friday.

The variant – which could be named ‘Nu’ by the World Health Organization in the coming days – has caused an ‘exponential’ rise in infections in South Africa.

Dr. Eric Feigl-Ding, an epidemiologist and senior fellow at the Federation of American Scientists, said initial data from the variant was worrying and border restrictions should be imposed.

‘Looks like vaccine evasion could be real with this variant,’ he tweeted, pointing out that the two patients in Hong Kong who had the variant were both doubled-jabbed with the Pfizer vaccine.

This chart shows the proportion of cases that were the B.1.1.529 variant (blue) and Indian 'Delta' variant (red) over time in South Africa. It suggests that the mutant strain could outcompete Delta in the province within weeks

This chart shows the proportion of cases that were the B.1.1.529 variant (blue) and Indian ‘Delta’ variant (red) over time in South Africa. It suggests that the mutant strain could outcompete Delta in the province within weeks

One of the two had recently been in Southern Africa. That person then passed it on to a second person, quarantining in the same hotel.

‘It’s very airborne,’ Feigl-Ding said. ‘The hotel guests were in different room across the hallway from each other. Environmental samples found the virus in 25 of 87 swabs across both rooms.’

He added: ‘I think border and travel restrictions make sense. Especially since Hong Kong only caught the case because of a mandatory hotel quarantine. Which countries in the west still have that??? Almost none.’ Botswana has four confirmed cases, South Africa 77 – with the real figure likely in the hundreds – and Hong Kong has two, meaning 83 cases of the variant are confirmed so far. But South African scientists tried to backpedal today saying it was ‘likely’ that vaccines still offered ‘high levels of protection’ against hospitalisations and deaths from the variant. Germany, Italy, the Czech Republic and the Netherlands joined Britain, Israel and Singapore in suspending travel from South Africa today and, in a sign of growing alarm, the European Union is also proposing prohibiting travel from the country and its neighbours.

As of 5:00 a.m. EST, the CDC website’s travel advice page for South Africa had the country listed as ‘Level 1: Low Level of COVID-19’, with flights to the US permitted from the African country since November 8. The levels range from Level unknown, Level 1: Low, Level 2: Moderate, Level 3: High and Level 4: Very High. The CDC page asks anyone travelling to and from South Africa to be fully vaccinated, or for those who are not to be tested for Covid. It also recommends travellers follow measures in-place in South Africa, including wearing a mask and social distancing. South Africa’s infection rate spiked 93 per cent in a day yesterday amid fears the strain is driving the surge. Local scientists say it has likely spread to all the country’s nine provinces, but there is yet to be a surge in hospitalisations in epicentre Johannesburg. Travellers from South Africa have been allowed entry into the US since November 8, when restrictions barring entry to people from more than 30 countries – implemented at the start of the pandemic – were partially lifted. The new rules, which came 19 months after the travel ban was implemented, require international visitors to show both proof of vaccination and a negative Covid test.

‘There’s a lot we don’t understand about this variant,’ said Richard Lessells, an infectious disease physician at the University of KwaZulu-Natal in Durban, South Africa, at a press briefing organized by South Africa’s health department on Thursday. ‘The mutation profile gives us concern, but now we need to do the work to understand the significance of this variant and what it means for the response to the pandemic.’ On Thursday Britain’s health secretary, Sajid Javid sounded the alarm over what one senior scientific advisor in the UK termed the ‘worst-ever’ super-mutant COVID variant.

He said it could make vaccines at least 40 per cent less effective, and as a result he said they had banned flights from South Africa and five other regional countries.

Experts explained earlier how the B.1.1.529 variant has more than 30 mutations – the most ever recorded in a variant and twice as many as Delta – that suggest it could be more jab-resistant and transmissible than any version before it.